Research

 

The SINGAPORE EYE RESEARCH INSTITUTE (SERI) is the national research institute for ophthalmic and vision research in Singapore. Serving as the research institute of the Singapore National Eye Centre, and directly affiliated to the Yong Loo Lin School of Medicine, National University of Singapore, as well the Duke-NUS Graduate Medical School, SERI undertakes vision research in collaboration with local clinical ophthalmic centres and biomedical research institutions, as well as major eye centers and research institutes throughout the world. There are 5 platforms:

 

 

1) Experimental and Basic Science Platforms

 

  • To focus on understanding the genetic basis and biochemical mechanisms of hereditary eye diseases, and includes the study of inherited glaucoma subtypes, corneal dystrophies, retinal dystrophies and myopia. Particular attention is given to eye diseases and phenotypes common to Asia such as primary angle closure glaucoma and myopia.

 

2) Clinical Trials and Research Platform with following groups:

  • Retinal Research Group
  • Glaucoma Research Group
  • Cornea & Refractive
  • Myopia
  • Occular Inflammation
  • Cataract

 

3) Translational Clinical Research Platform 

  • Translational Research Innovations in Ocular Surgery (TRIOS) Programme aims to  new wound healing drugs, novel anti-microbial peptides that possess low risk of drug resistance, new and more effective, sustained release drug delivery technology, innovative ultra-high resolution imaging devices for imaging ocular structures, advanced laser-assisted corneal transplantation surgery, clinical trials and genetic studies into the study of alternate therapy for treatment of primary angle closure glaucoma and identification of new genes in angle closure glaucoma.

 

 

4) Epidemiology Platform

 

  • Health Services Research Group

 

  • Singapore Epidemiology of Eye Disease (SEED)
    • Serves to initiate, promote and coordinate ophthalmic epidemiologic research in Singapore and throughout Asia. SEED aims to determine the epidemiology, impact and risk factors for visual impairment, cataract, myopia, glaucoma, age-related macular degeneration, and diabetic retinopathy.

 

  • SERI-NUHS

 

5) Ocular Imaging Research Group

  •     Forms a “one stop hub” for collaborative activities that will develop new software, read and grade images, test and validate the clinical utility of imaging software, and function as the first point of research in ocular imaging, and subsequently patient assessment, in terms of disease prediction, utilising new ocular imaging and elucidation technology. It will also form a focal point for initiation of commercialisation activities

 

 

For more information, please refer to SERI.

 

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